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RESEARCH PAPER / 2025-07-30

Proteomics Insights Into Gingival Aging: The Role of Oxidative Stress and Key Signaling Pathways.

Xiaomeng Liu, Boyuan Sun, Yixuan Jiang, Zhengyu Guan, Hongjiao Li

Department of stomatology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.Department of stomatology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. · pubmed

Abstract

Gingival aging is closely associated with oxidative stress, yet its molecular mechanisms remain poorly understood. This study employed proteomic analysis of gingival tissues from young and aged mice, combined with functional experiments, to elucidate the central role of oxidative stress in gingival aging and its underlying mechanisms.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The study claims that oxidative stress plays a central role in the molecular mechanisms of gingival aging. This research is relevant as it explores the underlying biological processes associated with aging, specifically focusing on oxidative stress, which is a known contributor to the aging process.

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