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RESEARCH PAPER / 2025-07-28

Larval diapause slows adult epigenetic aging in an insect model,

Erin E B Foley, Christian L Thomas, Charalambos P Kyriacou, Eamonn B Mallon

Department of Genetics, Genomics and Cancer Sciences, University of Leicester, Leicester LE1 7RH, United Kingdom.Department of Genetics, Genomics and Cancer Sciences, University of Leicester, Leicester LE1 7RH, United Kingdom. · pubmed

Abstract

Epigenetic clocks based on DNA methylation provide robust biomarkers of biological age, yet the mechanistic basis and functional significance of slowing these clocks remain unclear. Progress has been limited by the lack of short-lived, genetically tractable model organisms with functional DNA methylation systems. The jewel wasp,

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Research summary

The paper claims that larval diapause slows adult epigenetic aging in an insect model. This research is relevant as it explores mechanisms that may influence biological aging, potentially providing insights into the root causes of aging processes.

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