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RESEARCH PAPER / 2025-07-25

Developing a novel aging assessment model to uncover heterogeneity in organ aging and screening of aging-related drugs.

Yingqi Xu, Maohao Li, Congxue Hu, Yawen Luo, Xing Gao, Xinyu Li, Xia Li, Yunpeng Zhang

College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, 150081, China.College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, 150081, China. · pubmed

Abstract

The decline in organ function due to aging significantly impacts the health and quality of life of the elderly. Assessing and delaying aging has become a major societal concern. Previous studies have largely focused on differences between young and old individuals, often overlooking the complexity and gradual nature of aging.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper proposes a novel aging assessment model to uncover heterogeneity in organ aging and screen for aging-related drugs. This research addresses the complexity of aging and aims to assess and potentially mitigate the decline in organ function, which is central to longevity studies.

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