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RESEARCH PAPER / 2025-07-23

Effects of 12-week exercise on Meteorin-like levels, inflammation, and functional capacity in older adults: Korean national aging project randomized controlled study.

Parivash Jamrasi, Jun Hyun Bae, Wook Song

Department of Physical Education, Seoul National University, Seoul, 08826, Republic of Korea.Department of Physical Education, Seoul National University, Seoul, 08826, Republic of Korea. · pubmed

Abstract

Meteorin-like protein (Metrnl) is involved in regulating inflammation, metabolism, and muscle regeneration, making it a promising therapeutic target. Building on prior research, we investigated how exercise-induced changes in Metrnl relate to inflammatory markers, physical function, and cognitive performance. This randomized controlled trial examined the effects of a 12-week exercise intervention on circulating Metrnl, a novel biomarker, in 90 community-dwelling older adults (≥ 65 years).

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that a 12-week exercise intervention increases circulating Meteorin-like protein levels, which may relate to improved inflammation and functional capacity in older adults. This research is relevant as it explores the role of a novel biomarker in the context of exercise and its potential implications for aging and age-related functional decline.

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