Multi-omic profiling reveals age-specific blood biomarkers and aging-driven B Cell remodeling in osteoarthritis.

Bizhi Tu, Run Fang, Peizhi Lu, Mingxiang Liu, Shuo Yang, Dingtao Hu, Renzhi Ruan, Rende Ning

Department of Orthopedics, The Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei), 390 Huaihe Road, Hefei, Anhui, China. · pubmed

Paper

Abstract

Osteoarthritis (OA) pathogenesis involves age-related immune dysregulation, yet non-invasive diagnostic tools and mechanistic insights remain limited.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper identifies age-specific blood biomarkers and explores B Cell remodeling associated with osteoarthritis. This research is relevant as it investigates immune dysregulation linked to aging, which could contribute to understanding the biological mechanisms of aging and age-related diseases.

Author of this paper? Send a correction.