Sedentary lifestyle, physical activity, and aging: evidence from genetic correlation and mendelian randomization.

Chenke Jiang, Yihong Gan, Shengyu Chen, Jie Yao, Yilin Zhang, Yongsheng Fan, Xinchang Wang, Li Xu

School of Public Health, Zhejiang Chinese Medical University, Hangzhou, China.School of Public Health, Zhejiang Chinese Medical University, Hangzhou, China. · pubmed

Paper

Abstract

Observational studies have shown that physical activity and sedentary behavior are associated with aging. However, whether these associations underlie causal effects remains unknown. Thus, this study aimed to assess the genetic correlation and causal relationships between genetically predicted physical activity, sedentary behavior, and aging.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims to assess the genetic correlation and causal relationships between genetically predicted physical activity, sedentary behavior, and aging. This research is relevant as it explores the underlying causal mechanisms linking lifestyle factors to aging, which could inform strategies for longevity and age-related health improvements.

Author of this paper? Send a correction.