Effectiveness of mindfulness-based interventions on inflammaging: a systematic review and meta-analysis.

Xiaohong Huang, Jing Lv, Dongxu Zhu, Haining Peng, Tengbo Yu

Shandong Institute of Traumatic Orthopedics, Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, China.Shandong Institute of Traumatic Orthopedics, Medical Research Center, The Affiliated Hospital of Qingdao University, Qingdao, China. · pubmed

Paper

Abstract

Mindfulness cultivates awareness, presence, and non-judgmental acceptance, enhancing overall well-being. Inflammaging, linking age and aged-related diseases, manifests through heightened levels of IL-6, TNF-α, and CRP, impacting aging indicators like TA, TL, PWV, and FMD. To assess how mindfulness-based interventions (MBIs) affect inflammaging, a search was conducted in PubMed, Web of Science, Cochrane Central Register, and ProQuest Dissertation & Theses Global up to March 2024. Criteria included English articles and dissertations with participants over 18. Selected studies were randomized controlled trials (RCTs) and pre-post trials evaluating biomarkers related to inflammaging. Standardized mean differences were calculated using Morris's d

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Research summary

Mindfulness-based interventions can reduce biomarkers associated with inflammaging. The paper is relevant as it explores potential interventions that may address underlying mechanisms of aging rather than merely treating age-related symptoms.

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