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RESEARCH PAPER / 2025-07-16

Cool temperature inhibits binary fission and results in phenotypic and transcriptomic changes that suggest inducible aging in Diadumene lineata.

Clyde Eugene Makamure, Stephen Justinen, Daniel E Martínez, David A Hessinger, Isaac Kremsky

Department of Earth and Biological Sciences, Loma Linda University School of Medicine, Loma Linda, CA, 92350, USA.Department of Earth and Biological Sciences, Loma Linda University School of Medicine, Loma Linda, CA, 92350, USA. · pubmed

Abstract

Here we report initial observations and bioinformatics analysis suggesting that the sea anemone Diadumene lineata can be induced to age when cultured at 16

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Research summary

Cool temperature induces phenotypic and transcriptomic changes in Diadumene lineata that suggest a form of inducible aging. The study explores the mechanisms of aging in a model organism, contributing to the understanding of aging processes and potential interventions.

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