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RESEARCH PAPER / 2025-07-16

Sirtuins and their role in ovarian aging-related fibrosis predisposing to ovarian cancer.

Arkadiusz Grzeczka, Agnieszka Skowronska, Sara Sepe, Mariusz T Skowronski, Paweł Kordowitzki

Department of Basic and Preclinical Sciences, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Torun, Poland.Department of Basic and Preclinical Sciences, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University, Torun, Poland. · pubmed

Abstract

The pursuit of understanding early genetic or protein markers for ovarian aging has garnered considerable attention in the realm of reproductive medicine. Sirtuins (SIRTs) are a group of proteins that are NAD

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Research summary

The paper investigates the role of sirtuins in ovarian aging-related fibrosis and its connection to ovarian cancer. This research is relevant as it explores potential mechanisms underlying aging processes that could contribute to age-related diseases, specifically focusing on ovarian aging.

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