Association of a newly proposed dietary index for gut microbiota with phenotypic age acceleration: a cross-sectional study of NHANES 1999-2018.

Boming Xu, Yingxuan Huang, Yilin Zeng, Peizhong Chen, Yubin Wang, Xiaoqiang Liu

Department of Gastroenterology, First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, Fujian, China.Department of Gastroenterology, First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, Fujian, China. · pubmed

Paper

Abstract

Aging is closely linked to chronic diseases, and gut microbiota plays a significant role in this process. The Dietary Index for Gut Microbiota (DI-GM), a novel tool reflecting the potential impact of diet on gut microbiota diversity, has an unclear association with biological aging. This study aimed to evaluate the association between DI-GM and phenotypic age acceleration (PAA), revealing the potential regulatory effect of diet on aging.

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Research summary

The paper claims that a newly proposed dietary index for gut microbiota is associated with phenotypic age acceleration. This research is relevant as it explores the potential regulatory effect of diet on biological aging, addressing a root cause of aging rather than merely treating age-related symptoms.

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