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RESEARCH PAPER / 2025-07-12

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson's Disease-like Disorders in

Hui Li, Keqi Dong, Meihui Zhao, Ruifei Li, Chongli Shi, Chen Wang, Yaqiang Wei, Jiufeng Li, Lili Chen, Yanbin Zhao, Yu Li

Institute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China.Institute for Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China. · pubmed

Abstract

While 6:2 chlorinated polyfluoroalkyl ether sulfonate (F-53B) has been frequently detected in human samples and demonstrated to accumulate with age, its health risk for the elderly population remains unknown. Here, we evaluated the aging and neurodegenerative effects of F-53B using the

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that F-53B induces aging and Parkinson's disease-like disorders. The study addresses the potential health risks of a chemical that accumulates with age, linking it to neurodegenerative effects relevant to aging research.

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