The Trajectories of Neuromuscular Aging (TRAJECTOR-AGE Clinical Trial): Study Rationale and Methodological Protocol.

Fulvio Lauretani, Marcello Maggio, Andrea M Pilotto, Massimiliano Ansaldo, Clarissa M Brusco, Marco Carbonaro, Caterina Amendola, Marco Nabacino, Crescenzo Testa, Andrea Ciuni, Nicola Sverzellati, Irene Zucchini, Marco Salvi, Alfonso Mastropietro, Rebecca Re, Alberto Botter, Martino V Franchi, Simone Porcelli

Geriatric Clinic Unit, Medical Geriatric Rehabilitative Department, University Hospital of Parma, Parma, Italy.Geriatric Clinic Unit, Medical Geriatric Rehabilitative Department, University Hospital of Parma, Parma, Italy. · pubmed

Paper

Abstract

To examine the structural, metabolic, and functional trajectories of neuromuscular decline in aging and identify key mechanisms and early biomarkers to guide interventions preserving function and independence.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The study aims to identify key mechanisms and early biomarkers of neuromuscular decline in aging. This research is relevant as it seeks to understand and potentially mitigate the underlying processes of aging, rather than merely addressing symptoms.

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