Leg vascular function with advancing age in men: The impact of physical activity and endurance exercise training.
Abstract
Regular physical activity and endurance exercise training prevent age-related vascular endothelial dysfunction in the arm in men. However, the effects of physical activity and/or endurance exercise training in the legs, which have a greater predisposition for vascular disease, has not been completely elucidated. This study sought to examine the impact of aging, physical activity, and endurance exercise training on leg vascular function in men. Flow-mediated dilation (FMD) of the superficial femoral and popliteal arteries (SFA and PA, respectively) was assessed in a total of 39 men, comprised of 10 young sedentary (Y; 23±2 yrs), 8 older sedentary (OS; 76±8 yrs), 9 older physically active (OA; 71±8 yrs), and 12 older endurance exercise trained (OT) subjects with exceptional aerobic exercise capacity (V̇O
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Research summary
The paper claims that physical activity and endurance exercise training can prevent age-related vascular endothelial dysfunction in the legs of men. This research is relevant as it addresses the impact of lifestyle interventions on vascular health, which is a critical aspect of aging and longevity.
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