Acyl-CoA-binding protein as a driver of pathological aging.

Léa Montégut, Flavia Lambertucci, Lucas Moledo-Nodar, Carmen Fiuza-Luces, Carlos Rodríguez-López, Jose Antonio Serra-Rexach, Sylvie Lachkar, Omar Motiño, Mahmoud Abdellatif, Sylvère Durand, Fanny Aprahamian, Vincent Carbonnier, Delphine Le Corre, Sophie Mouillet-Richard, Hui Chen, Allan Sauvat, Yanbing Dong, Sijing Li, Yan Rong, Federico Pietrocola, Pierre Laurent-Puig, Carlos López-Otín, Isabelle Martins, Clea Barcena, Alejandro Lucia, Guido Kroemer

Team Metabolism, Cancer & Immunity, Centre de Recherche des Cordeliers, Equipe Labellisée par la Ligue Contre le Cancer, Université Paris Cité, Sorbonne Université, Inserm U1138, Institut Universitaire de France, Paris 76006, France. · pubmed

Paper

Abstract

The tissue hormone acyl coenzyme A-binding protein (ACBP, encoded by the gene

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Research summary

The paper claims that acyl-CoA-binding protein (ACBP) plays a significant role in driving pathological aging. This research addresses a potential mechanism underlying aging, which is relevant to understanding and potentially mitigating the root causes of aging.

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