Intermedin

Deng-Ren Ji, Rui Chang, Shi-Meng Liu, Ya-Rong Zhang, Jie Zhao, Yan-Rong Yu, Mo-Zhi Jia, Ning Wu, Hui-Fang Tang, Chao-Shu Tang, Ye-Bo Zhou, Yong-Fen Qi

Laboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing 100083, China; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing 100083, China; Department of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing 100083, China.Laboratory of Cardiovascular Bioactive Molecule, School of Basic Medical Sciences, Peking University, Beijing 100083, China; State Key Laboratory of Vascular Homeostasis and Remodeling, Peking University, Beijing 100083, China; Department of Pathogen Biology, School of Basic Medical Sciences, Peking University, Beijing 100083, China. · pubmed

Paper

Abstract

The aging-associated cardiac remodeling (AACR) is characterized by myocardial hypertrophy, fibrosis and cardiac dysfunction, which could be further aggravated by angiotensin II (Ang II) and pressure-overload in aged people. In this study, we aimed to investigate the roles and mechanisms of intermedin

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the roles and mechanisms of intermedin in the context of aging-associated cardiac remodeling. The study addresses a specific aspect of aging-related cardiac dysfunction, which is relevant to understanding and potentially mitigating age-related diseases.

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