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RESEARCH PAPER / 2025-07-03

Associations of metabolic obesity phenotypes with cognitive aging in middle-aged and elderly Chinese adults.

Yihui Li, Lei Yan, Pingting Yang, Jiangang Wang

Health Management Medicine Center, Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Hunan Engineering Technology Research Center for Sub-health Diagnosis and Intervention, Changsha, Hunan, China; Hunan Clinical Medical Research Center for Chronic Disease Health Management, Changsha, Hunan, China.Health Management Medicine Center, Third Xiangya Hospital, Central South University, Changsha, Hunan, China; Hunan Engineering Technology Research Center for Sub-health Diagnosis and Intervention, Changsha, Hunan, China; Hunan Clinical Medical Research Center for Chronic Disease Health Management, Changsha, Hunan, China. · pubmed

Abstract

Previous research has demonstrated that metabolic abnormalities accelerate cognitive aging. Although obesity is closely linked to metabolic disorders, it exhibits considerable heterogeneity depending on an individual's metabolic status. However, the relationship between this metabolic heterogeneity in obesity and cognitive aging remains unclear.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that metabolic obesity phenotypes are associated with cognitive aging in middle-aged and elderly adults. This research is relevant as it explores the relationship between metabolic health and cognitive decline, which are critical factors in understanding aging and potential interventions for age-related cognitive disorders.

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