The Chemical Exposome on Ovarian Aging in Adult Women: a Narrative Review.

Lauren M Petrick, Lauren A Wise, Elena Colicino, Megan K Horton, Jaron Rabinovici, Tzipora Strauss, Batya Sarna, Liat Lerner-Geva, Michal A Elovitz, Rosalind J Wright, Andrea A Baccarelli, Ronit Machtinger

Department of Environmental Medicine and Climate Change, Icahn School of Medicine at Mount Sinai, New York, NY, USA.Department of Environmental Medicine and Climate Change, Icahn School of Medicine at Mount Sinai, New York, NY, USA. · pubmed

Paper

Abstract

The effects of environmental exposures on female reproductive outcomes in early life are well studied. In contrast, we do not understand the broad range of chemical risk factors on women's reproductive physiology during midlife. The purpose of this review is to summarize the epidemiological literature on associations between environmental exposures (i.e., phthalates, phenols, per- and polyfluoroalkyl substances (PFAS), toxic metals, air pollution, and persistent organic compounds) and ovarian function and sex hormones as women approach and transverse the menopausal transition.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that various environmental chemical exposures are associated with ovarian function and hormonal changes in women during midlife. This research is relevant as it explores the impact of environmental factors on reproductive aging, which can contribute to understanding the broader mechanisms of aging and longevity in women.

Author of this paper? Send a correction.