Synergistic interaction and cumulative effect between frailty and triglyceride-glucose index exacerbate cardiovascular disease burden in middle-aged and older adults.

Menglu Liu, Jiawen Li, Kailun Yan, Kexin Zhang, Man Wang, Jidong Guo, Nuerbashati Heisha, Yuejin Yang, Jinqing Yuan, Yunqing Ye, Xueyan Zhao

National Clinical Research Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.National Clinical Research Center for Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. · pubmed

Paper

Abstract

Frailty and high triglyceride-glucose index (TyG) are independent risk factors for cardiovascular disease (CVD) and often coexist in middle-aged and older adults. This study aims to explore this influence in aging populations.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that the interaction between frailty and triglyceride-glucose index exacerbates cardiovascular disease burden in aging adults. This study is relevant as it explores the interplay of two significant risk factors in aging populations, contributing to our understanding of age-related health issues.

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