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RESEARCH PAPER / 2025-06-25

Association of peripheral immune markers with brain age and dementia risk estimated using deep learning methods.

Xiaxuan Huang, Shiqi Yuan, Yitong Ling, Shanyuan Tan, Zihong Bai, Yixian Xu, Si Shen, Jun Lyu, Hao Wang

Department of Anesthesiology, The First Affiliated Hospital of Jinan University, Guangzhou, China.Department of Anesthesiology, The First Affiliated Hospital of Jinan University, Guangzhou, China. · pubmed

Abstract

The peripheral immune system is essential for maintaining central nervous system homeostasis. This study investigates the effects of peripheral immune markers on accelerated brain aging and dementia using brain-predicted age difference based on neuroimaging.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The study claims that peripheral immune markers are associated with accelerated brain aging and dementia risk. This research is relevant as it explores the relationship between immune system markers and brain aging, which could contribute to understanding the biological mechanisms of aging and age-related diseases.

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