S-sulfhydration: Novel insights into the antioxidant and antiinflammation in age-related diseases.

Fei Liu, Lan Li, Longhui Yuan, Jingchao Yang, Xi Tang, Jingping Liu, Shuyun Liu, Younan Chen, Yanrong Lu, Jingqiu Cheng, Yujia Yuan

Department of Nephrology, National Health Commission (NHC) Key Laboratory of Transplant Engineering and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China; Department of Nephrology, Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China.Department of Nephrology, National Health Commission (NHC) Key Laboratory of Transplant Engineering and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China; Department of Nephrology, Institutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China. · pubmed

Paper

Abstract

Hydrogen sulfide (H

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Research summary

The paper claims that S-sulfhydration plays a significant role in mediating antioxidant and anti-inflammatory effects in age-related diseases. This research addresses mechanisms that could potentially mitigate the root causes of aging and age-related diseases, making it relevant to longevity research.

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