Stem Cell-Derived Extracellular Vesicles in Skin Antiaging Treatments.

Ji Yeong Park, Se Young Jung, Donghyeon Yoo, Sihun Lee, Dabin Go, Van Dat Bui, Won-Kyo Jung, Dong Gil You, Jae Hyung Park, Wooram Um

Department of Biotechnology, College of Fisheries Science, Pukyong National University, Busan 48513, Republic of Korea.Department of Biotechnology, College of Fisheries Science, Pukyong National University, Busan 48513, Republic of Korea. · pubmed

Paper

Abstract

As the median age of the global population rises and the demand for aesthetic enhancement increases, interest in antiaging skin technologies has been growing significantly. This review first addresses the molecular mechanisms underlying skin aging, followed by an overview of traditional antiaging approaches and their benefits and limitations. Furthermore, it emphasizes the potential of mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) as promising alternatives to address the shortcomings of conventional strategies. This article highlights the antiaging effects and therapeutic mechanisms of MSC-EVs in the skin microenvironment and identifies promising targets for skin antiaging interventions based on the functional properties of MSC-EVs. Finally, this review introduces the recent advances and future directions for MSC-EV-based antiaging strategies.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have potential antiaging effects on the skin microenvironment. This paper is relevant as it explores innovative approaches to address the mechanisms of skin aging, which aligns with the broader goals of longevity research.

Author of this paper? Send a correction.