Cellular Senescence in Human Chondrocytes in Relation to Osteoarthritis.

Yu Qiang, Chen Zheng, Alexander Y Maslov, Zhenzhen Lu, Min Zhou, Junjie Gao, Peijun Ren, Yidan Pang, Jan Vijg

Center for Single-Cell Omics, School of Public Health, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.Center for Single-Cell Omics, School of Public Health, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. · pubmed

Paper

Abstract

IntroductionCellular senescence, i.e., a state of permanent cessation of cell division, is a hallmark of aging and has been associated with age-related diseases, most notably osteoarthritis (OA). Here we assessed senescence in chondrocytes, first

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Research summary

The paper investigates the role of cellular senescence in chondrocytes and its relation to osteoarthritis. This research is relevant as it explores a potential underlying mechanism of aging that contributes to age-related diseases, specifically focusing on the cellular processes involved in osteoarthritis.

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