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RESEARCH PAPER / 2025-06-16

Foreign language learning in older adults modifies the pattern of resting-state activity in the medial prefrontal cortex.

Giovanna Bubbico, Federica Tomaiuolo, Carlo Sestieri, Golnoush Akhlaghipour, Alberto Granzotto, Giovanni Martinotti, Antonio Ferretti, Mauro Gianni Perrucci, Stefano L Sensi, Stefano Delli Pizzi

Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, Italy; Institute for Advanced Biomedical Technologies (ITAB), "G. d'Annunzio" University of Chieti-Pescara, Italy. Electronic address: [email protected]. · pubmed

Abstract

Foreign language learning (FLL) enhances cognitive functions in older adults, improving memory, attention, and executive functions and potentially delaying cognitive decline. However, the neural mechanisms underlying FLL's benefit on cognition remain unclear, and current methods for studying changes in brain activity are often operator-dependent, potentially missing important effects. This highlights the need for using data-driven techniques.

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Research summary

Learning a foreign language in older adults modifies resting-state activity in the medial prefrontal cortex. This research is relevant as it explores cognitive enhancement strategies that may contribute to delaying cognitive decline in aging populations.

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