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RESEARCH PAPER / 2025-06-08

Dietary ingredients inducing cellular senescence in animals and humans: A systematic review.

Lihuan Guan, Kristina Zdantsevich, Elena Sandalova, Karen C Crasta, Andrea B Maier

Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; NUS Academy for Healthy Longevity, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. · pubmed

Abstract

Cellular senescence (CS) is a hallmark of ageing and age-related diseases. While dietary interventions are often explored to reduce CS, less is known about dietary ingredients that induce it. This study systematically reviews the evidence on dietary ingredients that promote CS in animal models and humans.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims to systematically review dietary ingredients that promote cellular senescence. This research is relevant as it explores dietary factors that could influence the aging process and age-related diseases by focusing on a hallmark of aging.

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