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RESEARCH PAPER / 2025-06-07

Icariin Supplementation Alleviates Cognitive Impairment Induced by d-Galactose via Modulation of the Gut-Brain Axis.

Siju Li, Menghui He, Ying He, Tingting Jin, Jianwen Chen, Junkang Peng, Wenhao Hu, Feng He

School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, Guangdong 510006, China.School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou, Guangdong 510006, China. · pubmed

Abstract

Aging-related cognitive impairment seriously diminishes individuals' life quality. Icariin (ICA), a natural flavonoid separated from the herb

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Icariin supplementation can alleviate cognitive impairment induced by d-Galactose through modulation of the gut-brain axis. The study addresses cognitive impairment, which is a significant aspect of aging, and explores a potential intervention that may influence underlying mechanisms related to age-related cognitive decline.

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