Obesity paradox: association between lipid metabolism indices and skeletal muscle mass in older adults: the mediating role of uric acid.

Chaofan Sun, Xiaohui Yang, Xingzhong Feng

Beijing University of Chinese Medicine, Beijing, 100029, China.Beijing University of Chinese Medicine, Beijing, 100029, China. · pubmed

Paper

Abstract

This study aimed to explore the relationships between lipid metabolism indices-the Lipid Accumulation Product (LAP), Visceral Adiposity Index (VAI), Cardiac Metabolic Index (CMI), and Atherogenic Index of Plasma (AIP)-and sarcopenia in individuals aged ≥ 60 years, and to investigate the mediating role of uric acid (UA) in these relationships. The goal was to provide scientific evidence and practical guidance for preventing and treating sarcopenia in older adults.

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Research summary

The study investigates the relationship between lipid metabolism indices and sarcopenia in older adults, highlighting the mediating role of uric acid. This research is relevant as it addresses factors associated with sarcopenia, a significant age-related condition that impacts longevity and quality of life in older populations.

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