Pathophysiologically relevant bisphenol S exposure accelerates aging by disrupting brown adipose tissue-regulated energy metabolism.

Man Zhu, Ru Wang, Wei Yi, Beiyi Wu, Zhizhong Deng, Zheng Zhang, Chen Wang, Dingkun Zhang, Tongtong Zhang, Xue Wen

Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China. · pubmed

Paper

Abstract

Bisphenol A (BPA) substitutes are widely used as food contact materials and consumer products, while the effects of pathophysiologically relevant concentrations of BPA substitutes on aging remain unclear. In this study, we used

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Research summary

Pathophysiologically relevant bisphenol S exposure disrupts energy metabolism in brown adipose tissue, potentially accelerating aging. This study addresses the impact of environmental factors on aging processes, which is crucial for understanding and potentially mitigating the root causes of aging.

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