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RESEARCH PAPER / 2025-05-30

Sleep patterns and DNA methylation age acceleration in middle-aged and older Chinese adults.

Tingyue Diao, Kang Liu, Lue Zhou, Qiuhong Wang, Junrui Lyu, Ziwei Zhu, Fuchao Chen, Wengang Qin, Handong Yang, Chaolong Wang, Xiaomin Zhang, Tangchun Wu

Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, China.Department of Occupational and Environmental Health, Key Laboratory of Environment and Health, Ministry of Education and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hangkong Road, Wuhan, China. · pubmed

Abstract

Sleep is a biological necessity and fundamental to health. However, the associations of sleep patterns (integrating sleep determinants) with DNA methylation age acceleration (DNAm AA) remain unknown. We aimed to investigate the associations of sleep patterns with DNAm AA.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that specific sleep patterns are associated with DNA methylation age acceleration in middle-aged and older adults. This research is relevant as it explores the relationship between sleep, a fundamental biological process, and a biomarker of aging, potentially contributing to our understanding of aging mechanisms.

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