Metagenomics reveals an increased proportion of an

Jinyou Li, Yue Wu, Yichen Yang, Lufang Chen, Caihong He, Shixian Zhou, Shunmei Huang, Xia Zhang, Yuming Wang, Qifeng Gui, Haifeng Lu, Qin Zhang, Yunmei Yang

Zhejiang Key Laboratory for Diagnosis and Treatment of Physic-chemical and Aging-related Injuries, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.Zhejiang Key Laboratory for Diagnosis and Treatment of Physic-chemical and Aging-related Injuries, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. · pubmed

Paper

Abstract

Gut microbial communities are likely remodeled in tandem with accumulated physiological decline during aging, yet there is limited understanding of gut microbiome variation in advanced age. Here, we performed a metagenomics-based enterotype analysis in a geographically homogeneous cohort of 367 enrolled Chinese individuals between the ages of 60 and 94 years, with the goal of characterizing the gut microbiome of elderly individuals and identifying factors linked to enterotype variations. In addition to two adult-like enterotypes dominated by

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Research summary

The paper claims to characterize the gut microbiome of elderly individuals and identify factors linked to enterotype variations. This research is relevant as it explores the relationship between gut microbiome composition and aging, potentially shedding light on factors that could influence longevity and age-related physiological decline.

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