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RESEARCH PAPER / 2025-05-29

Brief guide to Caenorhabditis elegans survival assays.

Hyunwoo C Kwon, Seung-Jae V Lee

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea. · pubmed

Abstract

Caenorhabditis elegans is a versatile model organism widely used in survival assays to investigate aging, stress resistance, and pathogen infection. Here, we report an overview of survival assays using C. elegans, focusing on assay types, commonly used reagents, and notable analysis platforms. This MiniResource will provide practical information and insights for the design and application of C. elegans survival assays for researchers in the field.

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Research summary

The paper provides an overview of survival assays using C. elegans to investigate aging and stress resistance. The relevance lies in its focus on survival assays that can contribute to understanding the mechanisms of aging and longevity.

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