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RESEARCH PAPER / 2025-05-29

Brief guide to assays for measuring health parameters using Caenorhabditis elegans.

Seungjae Hwang, Jongsun Lee, Seung-Jae V Lee

Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, South Korea. · pubmed

Abstract

Assessing health parameters is essential for understanding the decline of physiological functions during aging. The nematode Caenorhabditis elegans serves as a powerful model in aging research. This paper introduces representative methods for evaluating health parameters using C. elegans and provides quantitative indicators of functional declines during aging. This manuscript will be useful for researchers unfamiliar with healthspan studies using C. elegans and may help perform physiological experiments for healthy aging.

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Research summary

This paper introduces methods for evaluating health parameters in C. elegans to assess functional declines during aging. The relevance lies in its focus on understanding physiological functions during aging, which is crucial for longevity research.

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