Nucleotides as an Anti-Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study).

Shuyue Wang, Lixia Song, Rui Fan, Qianqian Chen, Ruisheng Fu, Mei You, Yuxiao Wu, Meng Cai, Yong Li, Meihong Xu

Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, 100191, China.Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, 100191, China. · pubmed

Paper

Abstract

Aging impairs nutrient metabolism and accelerates biological aging, negatively affecting health and longevity. The Targeting Aging and Longevity with Exogenous Nucleotides (TALENTs) trial (ClinicalTrials.gov: NCT05243108) aimed to explore whether nucleotides (NTs) supplementation can delay biological aging and improve health outcomes in the elderly. The trial is a 19-week, double-blind, randomized, placebo-controlled study in Chengdu, China, with 121 participants (60-70 years). Participants are randomly assigned to either NTs (1.2 g day

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that nucleotide supplementation can delay biological aging and improve health outcomes in older adults. This study is relevant as it investigates a potential intervention aimed at addressing biological aging, rather than merely treating age-related symptoms.

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