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RESEARCH PAPER / 2025-05-23

Association of 24 h-movement behaviors with cerebral and hippocampal amyloid beta levels and executive function in cognitively normal older adults: a compositional data analysis from the AGUEDA trial.

Alessandro Sclafani, Jairo H Migueles, Marcos Olvera-Rojas, Patricio Solis-Urra, Beatriz Fernandez-Gamez, Andrea Coca-Pulido, Darío Bellón, Javier Fernández-Ortega, Javier Sanchez-Martinez, Lucía Sánchez-Aranda, Ángel Toval, Isabel Martín-Fuentes, Esmée A Bakker, Juan D Gispert, Eva M Triviño-Ibañez, Teresa Liu-Ambrose, Kirk I Erickson, Manuel Gomez-Rio, Francisco B Ortega, Irene Esteban-Cornejo

Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Spain. Electronic address: [email protected] of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Spain. Electronic address: [email protected]. · pubmed

Paper

Abstract

This study investigated the associations between movement behaviors (physical activity, sedentary behavior, and sleep duration), global and hippocampal amyloid beta levels, and executive function in cognitively normal older adults.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that specific movement behaviors are associated with amyloid beta levels and executive function in cognitively normal older adults. This research is relevant as it explores the relationship between lifestyle factors and biomarkers associated with cognitive aging, potentially contributing to understanding mechanisms that influence longevity and cognitive health in older populations.

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