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RESEARCH PAPER / 2025-05-22

Glycemic Variability and Control by CGM in Healthy Older and Young Adults and Their Relationship With Diet.

Anika Köhlmoos, Manuela Dittmar

Human Biology, Zoological Institute, Christian-Albrechts-University, Kiel 24118, Germany. · pubmed

Abstract

Continuous glucose monitoring (CGM) might be beneficial for investigating healthy aging since high glycemic variability may increase protein glycation, oxidative stress, and inflammation, resulting in vascular damage. Additionally, CGM data on the risks for hypoglycemia and hyperglycemia are scarce, have not been analyzed by individual day and night blocks, and have not been related to diet. Therefore, this study aimed to compare glucose parameters of healthy older and young adults and the relationship with diet. Participants were 34 young (age 20-35 years) and 27 older volunteers (age 60-75 years) with a normal glycated hemoglobin A

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Research summary

The study investigates the relationship between glycemic variability and diet in healthy older and young adults. This research is relevant as it explores factors that may influence healthy aging and metabolic health, which are critical components in understanding longevity.

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