Gut-vitamin D interplay: key to mitigating immunosenescence and promoting healthy ageing.
Abstract
Immunosenescence is the loss and change of immunological organs, as well as innate and adaptive immune dysfunction with ageing, which can lead to increased sensitivity to infections, age-related diseases, and cancer. Emerging evidence highlights the role of gut-vitamin D axis in the regulation of immune ageing, influencing chronic inflammation and systemic health. This review aims to explore the interplay between the gut microbiota and vitamin D in mitigating immunosenescence and preventing against chronic inflammation and age-related diseases.
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Research summary
The paper claims that the interplay between gut microbiota and vitamin D can mitigate immunosenescence and chronic inflammation associated with aging. This research is relevant as it addresses potential mechanisms that could influence the aging process and promote healthier aging by targeting immune dysfunction.
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