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RESEARCH PAPER / 2025-05-14

Three-year lifestyle changes, genetic risk, and risk of frailty among older adults: A national community-based cohort study.

Wen-Fang Zhong, Xiao-Meng Wang, Wei-Qi Song, Huan Chen, Jia-Hao Xie, Hao Yan, Jun-Jie Wang, Yue-Bin Lv, Zhi-Hao Li, Xiao-Ming Shi, Chen Mao

Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China.Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou, Guangdong, China. · pubmed

Abstract

The association between change in lifestyle in late-life and frailty mediated by genetic risk is yet to be elucidated. This study aimed to investigate the associations of change in lifestyle in late-life and genetic risk with frailty among older adults.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that changes in lifestyle in late-life can influence the risk of frailty among older adults, mediated by genetic risk factors. This research is relevant as it explores lifestyle modifications in the context of aging and frailty, which are critical aspects of longevity and age-related health outcomes.

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