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RESEARCH PAPER / 2025-05-14

Modulation of Sirtuins to address aging related disorders through the use of selected phytochemicals.

Jing Wang, Yaoyao Ren, Shengtao Qu

Department of Ophthalmology, Shengjing Hospital of China Medical University. 36 Sanhao Street, Heping District, 110004 Shenyang, Liaoning, PR China. Electronic address: [email protected]. · pubmed

Abstract

Aging is a complex phenomenon involving oxidative stress, inflammation, and cellular damage subsequently leading to various disorders, such as cardiovascular diseases, neurodegenerative disorders, diabetes, and cancer. Sirtuin (SIRT) proteins are one of the major molecular factors that affect human aging. Sirtuins are a class of NAD

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that modulation of sirtuins through selected phytochemicals can address aging-related disorders. The focus on sirtuins as a mechanism to potentially influence the aging process itself makes this research relevant to longevity.

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