Association of proBNPage with all-cause and cardiovascular mortality among US adults: an analysis of data from the National Health and Nutrition Examination Survey.

Zhe Zhou, Jiang He, Jing Ren, Yan Li, Chen Su, Xiaoyu Zhang, Yijia Shao, Wenhao Xia, Yan Wang, Fang Wu, Jun Tao

First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. · pubmed

Paper

Abstract

Biological age assessed by the Klemera and Doubal method (KDM) and phenotypic age (PhenoAge) was considered as a marker for ageing-related outcomes because it reflects different aspects of biological ageing and health, which are associated with increased risk of death. proBNPage based on N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a novel index for biological age estimation. However, the independence of its relationship with clinical outcomes from established risk factors, KDM or PhenoAge remains uncertain. Their identification could provide valuable information to prognosis.

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Research summary

The paper investigates the relationship between proBNPage and mortality outcomes, suggesting that proBNPage may serve as a novel index for biological age estimation. This research is relevant as it explores potential biomarkers that could provide insights into biological aging and its implications for longevity and health outcomes.

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