A Longitudinal Study of the Bidirectional Temporal Dynamics Between Body Mass Index and Biological Aging.

Peggy Ler, Jonathan K L Mak, Chandra A Reynolds, Alexander Ploner, Nancy L Pedersen, Juulia Jylhävä, Anna K Dahl Aslan, Deborah Finkel, Ida K Karlsson

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden.Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden. · pubmed

Paper

Abstract

Obesity and aging share biological processes, but their relationship remains unclear, especially in late life. Understanding how body mass index (BMI) and biological aging influence each other can guide strategies to reduce age- and obesity-related health risks. We examined the bidirectional, longitudinal association between changes in BMI and biological aging, measured by frailty index (FI) and functional aging index (FAI), across late life.

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Research summary

The paper claims that there is a bidirectional relationship between changes in body mass index and biological aging. This research is relevant as it explores the interplay between obesity and biological aging, which could inform strategies for addressing age-related health risks.

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