Physical resilience may offset mortality risks associated with genetic predisposition to shorter survival: A population-based cohort study.

Lea Stark, Federico Triolo, Davide Liborio Vetrano, Debora Rizzuto, Israel Contador, Amaia Calderón-Larrañaga, Serhiy Dekhtyar

Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden. · pubmed

Paper

Abstract

Physical resilience (PR), the ability to recover from health adversities, is thought to buffer health challenges during aging. However, PR's association with mortality and its ability to offset the negative effects of genetic susceptibility to shorter lifespan remain unknown.

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Research summary

Physical resilience may mitigate the mortality risks linked to genetic predisposition for shorter survival. The study addresses the interaction between physical resilience and genetic factors in relation to lifespan, which is pertinent to understanding mechanisms that could influence longevity.

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