Nutritional strategies targeting age-related skeletal muscle fibrosis: underlying mechanisms.

Iris Cuijpers, Joey Katsburg, Luc J C van Loon, Freddy J Troost, Mireille M J P E Sthijns

Department of Human Biology, Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands.Department of Human Biology, Institute of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, The Netherlands. · pubmed

Paper

Abstract

Aging is associated with a reduced number and function of muscle stem cells (MuSC). This results in a decreased muscle regenerative capacity and increased formation of fibrotic tissue, impairing skeletal muscle function. This review provides an overview of

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Research summary

Nutritional strategies can mitigate age-related skeletal muscle fibrosis and improve muscle function. The paper addresses the underlying mechanisms of muscle degeneration with age, focusing on potential interventions that could enhance muscle regenerative capacity, which is directly related to longevity research.

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