Oxidative stress and inflammation mediate the association between Life's Crucial 9 and biological ageing: A secondary analysis of two observational studies.

Haoran Wang, Jingwen Zhang, Jiaxin Ning, Yating Cui, Huimin Hou, Ming Liu, Jianyong Liu, Runhua Tang, Jianye Wang

Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. · pubmed

Paper

Abstract

Life's Essential 8 (LE8) is known to have a negative correlation with biological aging, while the relationship between the Life's Crucial 9 (LC9) score, which includes mental health, and biological aging remains to be further investigated.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that oxidative stress and inflammation mediate the association between Life's Crucial 9 and biological aging. This research is relevant as it explores factors that may influence biological aging, potentially addressing root causes of aging rather than merely treating age-related symptoms.

Author of this paper? Send a correction.