NAMPT regulates mitochondria and oxidative stress level for mouse early embryo development.

Mei-Hua Liao, Xin Liu, Xiao-Ting Yu, Shun Zhang, You-Zhu Li, Lin-Lin Hu, Shao-Chen Sun, Jun-Li Wang

Key Laboratory of Research on Clinical Molecular Diagnosis for High Incidence Diseases in Western Guangxi of Guangxi Higher Education Institutions, Reproductive Medicine of Guangxi Medical and Health Key Discipline Construction Project, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China. · pubmed

Paper

Abstract

Nicotinamide phosphoribosyltransferase (NAMPT) is an enzyme that involves into NMN-NAD + synthesis which involves into cellular metabolism related with aging, immune function, and neurodegeneration. However, its roles in early embryo development are still unclear.

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Research summary

NAMPT regulates mitochondrial function and oxidative stress levels during early embryo development. The study explores the role of NAMPT in cellular metabolism, which is directly linked to aging processes and could provide insights into mechanisms that influence longevity.

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