Exploring skin aging-associated genotypes; Moving toward delivery of precision medicine-based care more than beyond skin deep care: a genome-wide association study.
Abstract
Oxidative damage is the principal cellular disturbance in the skin aging. Missense polymorphisms strengthen or weaken detoxification enzyme activity. Determination of deleterious functional effects of polymorphisms in detoxification genes (NQO1 and EPHX1) in skin aging was the overall purpose of conducting this hospital-based research.
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Research summary
The paper claims that specific polymorphisms in detoxification genes are associated with skin aging. This research is relevant as it explores genetic factors that may contribute to the biological mechanisms of aging, potentially leading to precision medicine approaches in addressing skin aging.
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