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RESEARCH PAPER / 2025-05-03

Effect of calcitriol on myeloid-derived suppressor cells in physiological aging.

Yuliya V Perfilyeva, Aikyn Kali, Diana S Aben, Yulduz R Abdusattarova, Anzhelika V Lushova, Yekaterina O Ostapchuk, Raikhan Tleulieva, Anastassiya V Perfilyeva, Kamalidin O Sharipov, Timur I Davlyatshin, Nurshat Abdolla

M.A. Aitkhozhin Institute of Molecular Biology and Biochemistry, 86 Dosmukhamedov St., Almaty 050012, Kazakhstan; Almaty Branch of the National Center for Biotechnology, Central Reference Laboratory, 14 Zhahanger St., Almaty 050054, Kazakhstan. · pubmed

Abstract

The active hormonal form of vitamin D, 1,25(OH)

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that calcitriol influences the behavior of myeloid-derived suppressor cells in the context of physiological aging. This research is relevant as it explores the role of vitamin D in modulating immune responses that may contribute to aging processes, potentially addressing underlying mechanisms rather than just symptoms.

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