Associations of Accelerated Biological Aging With Dementia and the Mediation Role of Brain Structure: Findings From a Longitudinal Study.

Yacong Bo, Liuqiao Sun, Shengsheng Hou, Fenghua Zhang, Haowen Zhang, Xueyi Feng, Sisi Zhuo, Shiyu Feng, Hui Chang, Xiaoan Zhang, Zhengbin Wang, Zengli Yu, Xin Zhao

The Third Affiliated Hospital of Zhengzhou University, China.The Third Affiliated Hospital of Zhengzhou University, China. · pubmed

Paper

Abstract

The association between biological aging and dementia, as well as the underlying mechanism, remains limited. The aim of this study was to investigate the relationships of biological age (BA) with incident dementia and examine the underlying neurobiological mechanisms.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that accelerated biological aging is associated with the incidence of dementia and that brain structure mediates this relationship. This study is relevant as it explores the connections between biological aging and age-related diseases, contributing to the understanding of underlying mechanisms that could inform longevity research.

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