Early-life smoking, cardiovascular disease risk, and the mediating role of DNA methylation biomarkers of aging.

Chang Sheng, Rui Zhou, Hongcai Wang, Guoqiang Lin, Zhou Cai, Wei Wang

Department of Vascular Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.Department of Vascular Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. · pubmed

Paper

Abstract

Early-life smoking is linked to biological aging and chronic diseases, yet its specific relationship with cardiovascular disease (CVD) risk and the role of DNA methylation biomarkers of aging as potential mediators of that relationship remain underexplored.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Early-life smoking is linked to increased cardiovascular disease risk through the mediating role of DNA methylation biomarkers of aging. This paper is relevant as it explores the relationship between early-life behaviors and biological aging, contributing to our understanding of the mechanisms underlying age-related diseases.

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