Associations Between Female Sex Hormones and Skeletal Muscle Ageing: The Baltimore Longitudinal Study of Aging.

Annabel J Critchlow, Sarah E Alexander, Danielle S Hiam, Luigi Ferrucci, David Scott, Séverine Lamon

School of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition (IPAN), Deakin University, Geelong, Australia. · pubmed

Paper

Abstract

To date, most research investigating the influence of circulating sex hormones on ageing female skeletal muscle has been cross-sectional and focused only on dichotomised young and old, or pre- versus post-menopausal groups. This excludes an important transitional period from high to low circulating oestrogen. Using secondary data from the Baltimore Longitudinal Study of Aging, this study aimed to investigate cross-sectional and longitudinal associations between circulating sex hormones and skeletal muscle mass and function across a continuum of ages.

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Research summary

The paper claims that there are associations between circulating female sex hormones and skeletal muscle mass and function across a continuum of ages. This research is relevant as it explores the biological mechanisms of aging in skeletal muscle, which is a critical aspect of longevity and age-related decline.

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