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RESEARCH PAPER / 2025-04-28

TCF7-Linked Immune Resilience: A Salutogenic Biological Warranty for Longevity.

Rituparna Ghosh, Matthew J Yousefzadeh

Burch-Lodge Center for Human Longevity, Columbia Center for Translational Immunology, Columbia University Medical Center, New York, New York, USA.Burch-Lodge Center for Human Longevity, Columbia Center for Translational Immunology, Columbia University Medical Center, New York, New York, USA. · pubmed

Abstract

Immune resilience as a salutogenic force to preserve healthspan and resilience to challenges. The figure was created with BioRender (https://www.BioRender.com/).

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that TCF7 is linked to immune resilience, which can serve as a biological warranty for longevity. This research addresses immune resilience as a factor in healthspan and longevity, focusing on underlying biological mechanisms rather than merely treating age-related diseases.

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