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RESEARCH PAPER / 2025-04-26

Dyslipidemia and aging: the non-linear association between atherogenic index of plasma (AIP) and aging acceleration.

QianKun Yang, XianJie Zhu, Li Zhang, Fei Luo

National & Regional United Engineering Lab of Tissue Engineering, Department of Orthopedics, Southwest Hospital, Army Medical University, No.29 Gaotanyan St., Shapingba District, Chongqing, 400038, China. [email protected] & Regional United Engineering Lab of Tissue Engineering, Department of Orthopedics, Southwest Hospital, Army Medical University, No.29 Gaotanyan St., Shapingba District, Chongqing, 400038, China. [email protected]. · pubmed

Abstract

Dyslipidemia has been proved to play a pivotal role in biological aging. Atherogenic Index of Plasma (AIP), derived from serum triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C), is an effective biomarker of dyslipidemia. However, whether AIP can be used as an indicator of biological aging remains unclear. This study aims to investigate the relationship between AIP and biological aging in the US adult population.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the non-linear association between the Atherogenic Index of Plasma (AIP) and biological aging. This study is relevant as it explores a potential biomarker that could indicate biological aging, which is directly related to understanding the mechanisms of aging and longevity.

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